Predict the phenotype of embryos at the highest defensible resolution.
A Heru initiative to push embryo phenotype prediction across complex polygenic traits, built on the Haeckel dataset.
A dataset Haeckel alone can build.
Haeckel connects genotype, phenotype, and extended phenotype inside one consent-governed substrate. At scale, that becomes a world-unique dataset for calibrating embryo-level prediction with ancestry, family structure, environment, and uncertainty in view.
Polygenic trait calibration
Benchmark PRS methods, ensemble weights, ancestry correction, and confidence intervals trait by trait.
Embryo-level simulation
Model sibling distributions through Mendelian inheritance, recombination, parental genotypes, and phenotype priors.
Phenotype ontologies
Connect observable traits, biomarkers, morphology, cognition, disease risk, and longitudinal outcomes into one schema.
Validation
Use family data, held-out cohorts, and prospective follow-up to measure what prediction can and cannot claim.
A project for domain experts.
Research only. Not clinical advice. Any embryo work must be supervised and lawful where performed.